Parkinson’s disease has affected nearly ten million people all over the world and this is apart from causing mere movement disabilities. It is also responsible for adversely impacting their quality of life. The current approaches to treatment for Parkinson’s disease (PD) are mainly symptomatic, having very little emphasis on the reversing of its debilitating effects. Passing by the ebb and flow assortment of information, developments variations from the norm of Parkinson’s Disease start in the cerebrum where the dopamine creation, a synapse for development control, is irreversibly hindered, as an outcome neuronal demise. As of now, L-DOPA, a powerful PD medicine is basically recommended to renew dopamine in the denied mind. Be that as it may, such treatment is just symptomatic, as opposed to a malady adjusting treatment. Long haul utilization of L-DOPA is known to cause genuine symptoms, for example, automatic, whimsical, and squirming developments. Driven by Dr. C Justin Lee alongside Dr. Hoon Ryu and Dr. Sang Ryong Jeon, specialists at the Center for Cognition and Sociality of the Institute for Basic Science (IBS), Korea Institute of Science and Technology (KIST), and Asan Medical Center (AMC) separately, have found another instrument for PD pathology. The scientists revealed that the side effects of PD start when dopaminergic neurons are “non-useful”, even before they vanish. Despite the fact that the neuronal passing had been till now accepted to be the conspicuous reason for PD, the examination found that the development variations from the norm of PD start in the prior stage when dopaminergic neurons, however being alive, can’t combine dopamine (in a torpid state). The corresponding author of this study, Dr. Lee says that everybody has been engulfed in the typical idea of the neuronal death being the single cause of Parkinson ’s disease. That has hampered efforts for investigating the roles of several other neuronal activities like surrounding astrocytes.